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An important ROS regulator in cancer cells is the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2), whose activity is modulated by Kelch-like ECH-associated protein 1 (KEAP1), a ubiquitin ligase that mediates the degradation of NRF2 (see also above)

Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter Mutation That Decreases Antibiotic Susceptibility

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Morbidity and mortality: 2012 chart book on cardiovascular, lung, and blood diseases