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10,11 This compositional change affects host metabolism via the gutliver axis: conjugated bile acids act as antagonists of FXR in the intestine, inhibiting the intestinal FXR-FGF15/19 signaling pathway, leading to upregulation of hepatic cholesterol 7-hydroxylase expression and accelerating the conversion of cholesterol to bile acids, but may also promote hepatic lipogenesis

Traditional chinese formula xiaoyaosan alleviates depressive-like behavior in CUMS mice by regulating PEBP1-GPX4-mediated ferroptosis in the hippocampus

doi: 10.3389/fimmu.2018.00090 43 DonTABethonyJMLoukasA

Always read at eye level, using the bottom of the meniscus as your reference point

One way that the water activity of products in the mid and low water activity range can change is due to moisture migration