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Do I need to do any preparation before the course

We describe a child with TC deficiency who presented with classical clinical and lab stigmata of inborn error of vitamin B12 metabolism except normal serum B12 levels

Damage to mitochondrial DNA, reduced efficiency of the electron transport chain, changes in substrate utilization, and impaired mitochondrial quality control cumulatively exacerbate oxidative stress in a self-reinforcing cycle that accelerates cardiometabolic disease progression (3, 4)

Christensen, L

Notably, blood tests showed that MAP30 did not impair liver or kidney function in MAP30-treated mice (102)