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The optimized nanosuspension (particle size = 134.0 0.6 nm, PDI = 0.179 0.021, physical stability = 72 0 h, and encapsulation efficiency of FIN = 90.67 0.08%) was subsequently spray-dried into a dry powder, which exhibited excellent redispersibility (RdI = 1.09 0.04) and satisfactory drug deposition in the olfactory region using a customized 3D-printed nasal cast (45.4%) and an Alberta Idealized Nasal Inlet model (8.6%) at 15 L/min

Vongpradith A

The gel was stained with Coomassie brilliant blue R-250 to visualize protein

Passive targeting by liposomes can be achieved to minimize drug accumulation in healthy tissues, reduce toxicity, and improve local therapeutic effects[107]

There is an urgent need to carry out long-term randomized controlled trials in relevant populations to promote the clinical application of R