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NRF2 protein is unstable under basal conditions, being ubiquitinated by an E3 ubiquitin ligase kelch-like ECH-associated protein-1 (KEAP1) and subsequently undergoing rapid degradation through the proteasome pathway

Participants completed cognitive testing and serial MR imaging over 5 years and underwent a lumbar puncture for CSF collection

Han Y-M, Jeong M, Park J-M, et al

10.5603/AH.a2021.0019 Arterial Hypertension 123 ZarezadehM.BarzegariM.AghapourB.AdeliS.KhademiF.MusazadehV.et al (2022)

WangYZhouXZhaoDWangXGurleyECLiuRet alBerberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes