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impurities, concentrations of the conversion product, diketopiperazine (SC-19192), ranged from 0.8% to 1.2%) at a dose of 0 (control), 1, 2, or 4 g/kg body weight (bw) per day, adjusted according to body-weight change, for up to 104 weeks

a prophylactic dose dose contemplates a dose that may be slightly less than the normal minimum amount of a pharmaceutical drug that will treat a biological or medical event that is sought to be overcome in a tissue, a system, animal or human by a researcher, veterinarian, medical doctor or other clinician, and addresses the problem of minimizing the toxicity of many drugs while having at least some of the drug present in the mammalian system to reduce the time before effective treatment by a drug begins

10.1186/s12974-016-0752-y 53

[11] [12] Genetics [edit] Alcohol flush reaction is a condition that is experienced more frequently by people of East Asian descent, giving rise to names such as "Asian flush" or "Asian glow"

This pathway is active during brain development and plays a role in neural repair after injury