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Given that ferroptosis results in cellular rupture and exacerbates inflammation, it remains unclear whether HO-1-induced ferroptosis could establish a positive feedback loop that drives disease progression

In addition, our previous work also showed that retinal L-acetylcarnitine was elevated after optic nerve crush in mice 32

For Metabolomics and lipidomics data analyses, centroided and integrated mass spectrometry data from the UPLC-TOFMS were processed using XCMS (Scripps Institute) to generate a data matrix containing ion intensities, mass to charge (m/z) and retention time values

& Klein, R

Eventually, a synergistic effect by appropriate O 2 delivery and enhanced radiosensitization of Gd-Tex has been demonstrated