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Description

Reported dose-dependent limitation of weight and fat-mass gain, improved glucose tolerance and insulin sensitivity, reduced hyperinsulinemia, and improvements in steatosis and liver markers

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Int J Mol Sci (2021) 22(11)

MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Injection-site reactions Generally well-tolerated in published Phase 1/2 data No IGF-1 elevation (key distinction from rhGH or GH-axis peptides) Known interactions No major drug-drug interactions documented in published data Contraindications Pregnancy/lactation (unstudied) Hypersensitivity REGULATORY STATUS FDA Not FDA-approved