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Third, dopaminergic neurons have increased vulnerability to oxidative stress because they produce a large amount of dopamine, which can be oxidized by ROS, subsequently resulting in lysosomal dysfunction and -synuclein accumulation 9

The perfusion rate was accordingly selected to microvascular shear stress of 0.10.5 dyn/cm 2 found in the human liver sinusoid in vivo 28,75,76

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Many patients report feeling more energized, focused, and resilient

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