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doi: 10.3389/fncel.2015.00519 95 KhanS

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(2000) PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

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We confirmed the previously reported increase in insulin secretion and glucose disposal [25] but failed to detect a differential response between WT and KO mice (ESM Fig

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