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Drug concentrations required to reduce viral cytopathic effect by 50% (EC50) were calculated using nonlinear regression from plots of percentage cell viability versus log 10 drug concentration using GraphPad Prism v.9.5.1 (GraphPad Software)

In this case, Vma2 could be efficiently degraded under the same YPD + 3-IAA protocol (Supplementary Fig

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KPV adds an anti-inflammatory signaling dimension to the tissue biology profile of the other three components

The GCL from Trypanosoma brucei and the mammalian catalytic subunit share 45% amino acid identity, but the T