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A study proved that p53 could bind to dipeptidyl-peptidase 4 (DPP4) to reduce the DPP4-dependent oxidization of PUFAs to inhibit ferroptosis in colorectal cancer cells[46]

Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR)

Reactive Oxygen Species (ROS) kit, DAPI and Calcein AM were purchased from Beyotime Biotechnology Corp., Ltd

This section delineates SFNs multifaceted mechanisms across epigenetic regulation, programmed cell death pathways (particularly ferroptosis), and tumor immune microenvironment remodeling, establishing its role as a truly multi-targeted therapeutic agent

Mass Spectrometry (MS) Alignment: We run mass spec diagnostics to confirm the exact molecular weight of each component, ensuring zero degradation or incorrect molecular bonding occurred during the freeze-drying process