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This typically occurs during a new complaint evaluation or when medical decision-making is complex

They were originally discovered in bone marrow but were later found in many other adult tissues, such as adipose tissue and placenta

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One cluster analysis of 131 ME/CFS patients diagnosed according to the Fukuda criteria revealed that 34% of patients experienced sympathetic symptoms with dysautonomia (and were associated with more severe disease severity), 5% from sympathetic symptoms alone, 21% parasympathetic, and 40% struggled with sympathovagal balance (331)