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Besides, it triggers the release of pro-inflammatory cytokines like NF-kB, IL-6, IL-1, and TNF- as well as the activation of many pro-inflammatory signaling pathways via ROS-driven mechanisms

We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig