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Bharti R, Sharma R (2022) Effect of heavy metals: an overview

Moreover, it was postulated that the aromatic ring of the 3-homotyrosine side chain and the C-terminal phenyl ring interact and Phe550 in IRAP further stabilizes aromatic/hydrophobic packing (Barlow et al., 2020)

The major role of GST is cellular detoxification via conjugation of glutathione (GSH) to endobiotic and xenobiotic compounds, increasing their solubility and facilitating their excretion from the cell (Mannervik et al., 1988