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The patients (mean age: 52 years) were treated either with an 8-week intervention of high cocoa liquor/polyphenol rich chocolate or simulated iso-calorific chocolate (cocoa liquor free/low polyphenols) with a wash-out period of 2-weeks followed by an 8-week intervention of other chocolate

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10.1146/annurev-biophys-083012-130324 15 AndoT.UchihashiT.ScheuringS

Bio-Synthesis of Coenzyme Q10 Reduced by Ageing and Statin Medications Supplementation is necessary to achieve greater concentration of CoQ10 because the ageing process, the use of certain medicines such as the statin medications, and the development of some diseases will cause a reduction in the body's bio-synthesis of Coenzyme Q10