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doi: 10.2337/diacare.24.4.733 10 SakurabaHMizukamiHYagihashiNWadaRHanyuCYagihashiS

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& Akkari, L

Ann N Y Acad Sci 1258:3442

Conversely, an adequate supply of BH4 can restore eNOS functionality, enhance NO production and inhibit ROS generation, thus alleviating inflammation and senescence in endothelial cells (34)