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TRANSCRIPT CLASSIFICATION To assess transcript novelty, the IsoQuant-derived GTF file was analyzed using SQANTI3 v5.5.1( 28 SQANTI3 classified each transcript as known or novel (e.g., NIC, NNC) by comparing it with the reference annotation and reported splice junction quality metrics

Additional sympathetic and spinal afferent nerves connect the gut to the spinal cord, conveying visceral pain or discomfort and modulating gut immune activity [22]

66,168 Such tools represent a paradigm shift toward precision proteostasis engineering

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The GCLM subunit has no enzymatic activity but has an important regulatory function increasing the efficiency of the GCLC subunit