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CrossRef MiR92a regulates brown adipocytes differentiation, mitochondrial oxidative respiration, and heat generation by targeting SMAD7 Zhipin Zhang, Huixin Jiang, Xiang Li, Xiaomin Chen, Yihua Huang Journal of Cellular Biochemistry.2020

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Importantly, after 3 days of intratracheal administration of BUD, LNPs, and BUD-LNPs, the levels of ALT, AST, AKP, BUN, CRE and UA showed no significant differences compared to the control group, indicating that intratracheal administration of BUD-LNPs (contained BUD 0.5 mg/kg) did not cause significant hepatotoxicity and nephrotoxicity (Figure 8bg)

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