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Both Heffernan papers showed significant reductions in body weight gain, increased fat oxidation measured by indirect calorimetry, and elevated plasma glycerol (a marker of active lipolysis) in obese mice

So I think your point, Michael, that we need to look at outcomes, is very important, and I do use the research

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Tirzepatide primary mechanism involves GLP-1 and GIP receptor activation, which suppresses appetite