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The mutation leading to Friedreichs ataxia is a repeated stretch of three DNA bases, GAA, located in the first part of the frataxin gene

Subcellular tracking via immunofluorescence analysis showed that biotin-conjugated butyrate primarily accumulated in lysosomes in A549 and H1299 cell lines [47]

Insulin-like growth factor-II is increased in systemic sclerosis-associated pulmonary fibrosis and contributes to the fibrotic process via Jun N-terminal kinase- and phosphatidylinositol-3 kinase-dependent pathways

Apocynin, a NOX2 inhibitor, prevented motor neuron loss caused by SOD1-mutated astrocytes in vitro [38]

So far, eight different isoforms of glutathione peroxidase (GPx1-8) have been identified in humans