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With regard to the substantial clinical improvement criterion, the applicant asserted that TECVAYLI TM represents a substantial clinical improvement over existing technologies because its indication is less restrictive than some other treatments, making it available to patients who do not qualify for the other drugs that treat RRMM

GO analyses showed that genes associated with the 732 hyper-DMRs are highly enriched in metabolic pathways, such as RNA metabolism, fatty acid oxidation, and lipid oxidation

The strong antioxidant activity of pomegranate juice has been largely attributed to ellagitannins, particularly punicalagin, whose concentrations are approximately threefold higher than those found in green tea infusions or red wine (365)

However, like any intravenous treatment, it carries minor risks, including: Temporary nausea or dizziness Allergic reactions (rare) Skin rashes Mild pain at injection site Dr

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