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Safety & Tolerability Preclinical Findings : IGF-1 LR3 demonstrates potent biological activity but requires strict dosing in experimental settings

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The in vivo process of GAA elimination from the CSF was partially inhibited by CT and taurine [50, 56]

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Likewise, NAD depletion contributes to oxidative stress, as NAD enhances antioxidant capacity by increasing glutathione levels and antioxidant enzyme activity (209)