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Cellular annotation markers and their distribution among different cellular sub-clusters were also labeled ( Supplemental Figure 1, Supplemental Table 1 and 2 )

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Depending on the core substrates that provide ribosyl and niacinamide, the current biocatalytic method is divided into two main types: one is based on the synthesis of NMN using PRPP and NAM as core substrates with the key enzyme NAMPT (Maharjan et al., 2021) and the other one is that NRK catalyzes the phosphorylation of NR with ATP to produce NMN (Cheng et al., 2024)

In contrast, the MSD of SERF2 molecules in higher-order condensates was much slower, with diffusion constants ranging from ~0.3 to 5 m 2 /s (Supplementary Fig