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Malaguernera, M., Bella, R., et al

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Some studies have shown that when combined with nitrites, potassium sorbate have genotoxic activity in vitro

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In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]