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Afr J Pharm Pharmacol 7(40):27012709 El-Marasy SA, Farouk H, Khattab MS, Abdelbaset M (2025) Protective effect of roflumilast on cyclophosphamide-induced ovarian toxicity in rats: role of SIRT1/Nrf2/nF-B pathway

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MTH1 has been identified as a pivotal driver of this vascular remodeling in PAH patients and in animal model cells and tissues