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doi: 10.1001/jama.2020.2648 149 BednashJSKaganVEEnglertJAFarkasDTyurinaYYTyurinVAet al

Through this connection, TB4 has been studied for its potential to support cell regeneration, promote healthy blood-vessel development, and modulate inflammatory responses

Cell 167 , 15981609 (2016)

These findings provide direct evidence of local iron accumulation and oxidative stress in the human fibrotic lung, reinforcing the pathophysiological rationale for targeting iron in therapeutic strategies