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Digestive symptoms in COVID-19 patients with mild disease severity: clinical presentation, stool viral RNA testing, and outcomes

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58 During the progression from preneoplastic glycogenotic to glycogen-poor neoplastic cell populations, this process is linked to an isoenzyme shift from the pyruvate kinase characteristic of normal hepatocytes (PK-M 1 ) to PK-M 2 , 45,59 which is critical for regulating the glycogen shunt flux