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Many mucocutaneous findings, including hair and nail changes and hyperpigmentation, especially of the hands and feet, are associated with vitamin B12 deficiency [5]

Some researchers also track NAD+ metabolite levels via urinary nicotinamide excretion to confirm functional NNMT inhibition, though this is not standard practice

B12 also helps with nerve metabolism and energy production to ensure proper nervous system functioning

Pernicious Anemia: The Autoimmune Cause Hiding in Plain Sight Pernicious anemia is an irreversible autoimmune disease in which the body attacks the parietal cells of the stomach, destroying intrinsic factor production

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