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Several reasons may explain the observation that the mean treatment difference was 12.5% in STEP 1 and 8.7% in SELECT

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FIGURE 2 3.2 NNMT and diabetes Diabetes is caused by a fundamental disturbance in the metabolism of glucose and is characterised by IGT, elevated fasting blood glucose, and inadequate insulin secretion or IR (Tripathi and Srivastava, 2006

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