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Scientists have found pharmaceutical residues in freshwater ecosystems across the world, where they may affect fish behavior, reproduction, and aquatic biodiversity

FDA identified particular concern for proposed injectable exposure because no clinical immunogenicity or aggregation studies were available

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How do hemodynamic changes regulate the uPA activation is still unclear

gingivalis has been shown to alter the gut microbial composition and suppress the expression of TJ-related proteins, thereby augmenting the systemic translocation of bacteria and their products (84, 85)