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Thus, intranasal formulations should be carefully balanced with safety considerations and clinical success, rather than relying heavily on permeation enhancers to achieve effective, well-tolerated therapy (Qiu et al., 2025)

Long-term health issues related to heavy alcohol use: Chronic high BAC levels can lead to serious health problems, including liver disease, brain damage, and heart problems

This approach captures the broader diagnostic categories (e.g., E11.1 was reduced to E11), ensuring that key information is retained without overcomplicating the model with finer diagnostic subcategories that may add redundancy or noise to the data

The most common way to prevent or fix a deficiency is by getting vitamin B12 shots