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Br J Pharmacol 134:14291436 Bae M, Roh J, Kim Y, Kim S, Han H, Yang E, Kang H, Lee S, Kim J, Kang R (2021) SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function

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Although several studies suggested that cystic fibrosis and noncystic fibrosis epithelia have similar expression of TLRs 40, 41 , alterations in receptor localization could result in key differences in TLR-initiated signaling between the two types of epithelia

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In conclusion, environmental pollution disrupts microbial ecology and immune homeostasis through multiple pathways, providing modifiable risk targets for the prevention, prediction, and intervention of IBD