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Ultrasmall peptide-coated platinum nanoparticles for precise NIR-II photothermal therapy by mitochondrial targeting

A phase-3 study was conducted to evaluate the safety and efficacy of VM202 in DPN

[] Ascorbic acid is a vinylogous carboxylic acid, which consists of the vinyl double bond that transports electron pairs between the hydroxyl and carbonyl groups as shown in Figure 9

Taken together, in the current study, the combination therapy of SE with AST and PHA exerted more favorable actions in all the measured behavioral outcomes, neurotransmitters levels, biochemical parameters, together with histopathological findings, compared to any other group in this study

The tumor size was measured twice per week, and the tumor volume was calculated according to the flowing equation: volume = length width 2 /2