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Notably, protein aggregates can interfere with the function of iron-sulfur clusters (Prasad Panda and Kesharwani, 2023)

6.5 Mechanical stress In intervertebral disc (IVD) tissue, cells are continuously subjected to various mechanical stresses including compression, tension, shear, torsion, and hydrostatic pressure

Clinical studies have shown that early postpartum women with peripartum cardiomyopathy exhibit significantly higher CD38+ cells compared to postpartum women without cardiomyopathy [36]