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Interestingly, ZIP13-deficient mice show increased biogenesis of beige adipocytes due to accelerated differentiation of preadipocytes into beige cells, suggesting that ZIP13 physiologically acts as a negative regulator of adipocyte browning

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3.2 Failure of the DNA repair mechanism Approximately 97% of N7-MeG adducts are eliminated from pyloric mucosa within 48 hours following MNNG exposure, possibly attributable to active base excision repair (BER) (21)