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Recreational Nitrous Oxide Abuse Induced Vitamin B12 Deficiency in a Patient Presenting with Hyperpigmentation of the Skin PMC Vitiligo Treatment: From Ointments to Depigmentation New Vitilox Vitamins and T Cell V Vitilox for Vitiligo Treatment Which Vitamin Deficiency Causes White Spots on the Skin? Glossitis and hyperpigmentation of hands due to Vitamin B12 deficiency. B12 leads to melanin synthesis more frequently in people with darker skin. Skin hyperpigmentation was reversed with B12 replacement

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