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As we age, NAD levels naturally declineleading to fatigue, brain fog, and slower recovery

Consequently, this leads to Ca 2 + dyshomeostasis and mitochondrial depolarization, cytochrome c release and apopotosome formation, permeabilization of the outer mitochondrial membrane as well as causing the hyperproduction and release of O 2 and H 2 O 2 leading to other free radical damage 70