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Despite great interest in repurposing the antimalarial hydroxychloroquine as a lysosomal inhibitor in clinical oncology trials, the mechanisms by which hydroxychloroquine and other lysosomal inhibitors induce tumor-cell cytotoxicity remain unclear

Conversely, TP53 can suppress ferroptosis by inhibiting dipeptidyl peptidase 4 (DPP4) activity or inducing cyclin dependent kinase inhibitor 1A ( CDKN1A , also known as p21) 157,158

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Differential diagnosis is important to determine the correct therapeutic intervention and includes Rathkes cleft cysts, non-prolactin secreting cystic adenomas, craniopharyngiomas, and arachnoid cysts (40)

Referring to glutathione as the master antioxidant isnt just a catch phrase