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In a pilot study in Thailand, Sangsuwan and Asawanonda tested the influence of daily intake of oral collagen (5 g) for 4 weeks on skin elasticity, especially in sun-exposed areas, in a randomized, double-blind, placebo-controlled trial (in a total of 36 women, aged 4060 years, where one-half of the participants were in the treatment group [ n = 18] or the placebo group [ n = 18]) [39]

doi: 10.1016/j.celrep.2017.01.063 126 SokerSTakashimaSMiaoHQNeufeldGKlagsbrunM

137 Similar positive results have been observed in several other studies

The practical effect of longer duration is that trials can measure outcomes over weekly and multi week windows with consistent exposure, rather than focusing only on short time course endpoints