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In RA patients, there are no associations between vitamin B6 intake and plasma PLP, no indication of congenital defects of vitamin B6 metabolism (34, 36, 168) and no vitamin B6 deficiency as judged by other B6 markers, like erythrocyte aspartate transaminase activity coefficient (EAST-AC) (191), erythrocyte PLP (36) or urinary PA excretion (36)

For instance, nanoparticles can be engineered to target specific cells or tissues, potentially increasing vaccine efficacy while minimizing adverse reactions