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Description

Med Sci Monit 2015;21:2414-20

Double-blind, placebo-controlled study of HGF gene therapy in diabetic neuropathy

Phase Continued therapy Timing Daily Daily Dose 2 mg Notes Trials showed effects reverse when stopped

To evaluate the expression levels of the mitochondrial carriers YlCrc1 and YALI0A20988p, and of the two putative CATs YlCat2 and YlYat1, a qPCR analysis was performed in the wild type strain grown on YNB medium supplemented with either 40 g/L glucose or oleic acid as carbon source

Acute pancreatitis has been reported with incretin-based therapies, and patients with a history of pancreatitis may be at increased risk for recurrence