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The role of NAD + in immunomodulation is context and signaling pathway specific

Ognjanovi BI, Markovi SD, Ethordevi NZ, Trbojevi IS, Stajn AS, Saici ZS (2010) Cadmium-induced lipid peroxidation and changes in antioxidant defense system in the rat testes: protective role of coenzyme Q(10) and vitamin E

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Downregulating MYCN in IMR-5/75 decreased caspase activation for both treatments, while inducing MYCN expression in SH-SY5Y/MYCN increased caspase activation, although the differences were not statistically significant ( Figure 4D )