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These and other reviews on the pharmacological properties of individual 1,4-NQ-producing species, including Henna, 205208 Plumbago seylanica 209 and Venus fly trap, 210 or individual 1,4-NQs of plant origin, such as the alkannins and shikonins, 90,211214 plumbagin and its analogs, 215 7-methyljuglone, 216 and laphachol, 16 demonstrate the considerable pharmacological interest in this class of molecules in recent years