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Angelice GP, Roque PH, Valente G, Galvo K, Villar LM, Mello VM, et al

Stopping ART is not a good idea, as HIV can come out of hiding and begin to damage the immune system

This in turn regulates the stability of phosphoglycerate dehydrogenase (PHGDH) and subsequently the anti-apoptotic protein Bcl2 (Gao et al., 2021)

This article covers the exact physiological rationale for morning dosing, what happens when you dose at night instead, and the preparation mistakes that negate timing benefits entirely