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Additionally, the reduction in -amyloid (1-40) levels in animals supplemented with PXN HIGH and CAF HIGH suggests a potential mechanism for the cognitive benefits observed

The mechanism by which activated platelets induce thrombosis in -thalassemia/HbE disease has not been fully elucidated

The WNT proteins present in the extracellular space bind to receptor frizzled and coreceptor lipoprotein-like receptor protein (LRP) 5/6 present on the cell surface of mesenchymal progenitors

The DNA sequencing data from patients and PDXs used in this study has been deposited in the European Genome-Phenome Archive under accession code EGAS00001006494