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b - d , 3-month-old Mx1-Cre and Mx1-T3 mice were treated with -glucan or PBS and Lineage-negative cells were harvested 7 days later, differentiated into myeloid cells, treated with -glucan or PBS, further differentiated before LPS induction for 24 hr for cytokine production

To improve efficacy and reproducibility, future research should focus on the standardization of herbal compounds, optimization of clinical trial design, and adoption of integrative approaches that combine herbal therapies with conventional pharmacological treatments

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In HIV infection, glucose metabolism is significantly upregulated, as evidenced by increased glucose transport and metabolic flux (103, 104)