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In lung cancer, SHMT1 and SHMT2 are both highly associated with the infiltration of different types of immune cells, and are potential prognostic biomarkers [57, 58]

It is possible to confirm the potential of biological activities using Cell-based methods

Their mechanism of action is mainly to inhibit the renin-angiotensin system (RAS), reduce the production of angiotensin II, and effectively improve endothelial cell function ( , IL-6) and pro-fibrotic factors, delay the fibrosis process of renal disease, and protect renal function ( 5.2 Cell therapy and gene therapy As an emerging cell therapy strategy, EPCs transplantation has brought new prospects for the treatment of renal diseases ( Gene therapy uses modern molecular biology technology to introduce specific functional genes into endothelial cells through vectors such as adeno-associated virus (AAV), lentivirus, or small interfering RNA (siRNA)

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pylori is particularly helpful in reversing MALT lymphoma either in the early MALT stage or in the late bone marrow-involved stage