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To further investigate the histological alterations and the expression of tumor-related proteins in tumor tissues, H&E staining and immunofluorescence staining were conducted on the B16F10 tumor tissues

This includes the proliferation and expansion of T cells at the ocular surface, causing damage, reactivation of acute pro-inflammatory innate responses, and, as immune regulation is lost, a vicious cycle of pathological immune reactions [106, 107]