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In a phase II clinical trial Ataluren showed an improvement in the forced expiratory volume in 1 s (FEV 1 ), although subsequent trials confirmed a slight improvement in FEV 1 only in a subgroup of patients (Tosco et al., 2018)

Notably, clinical trials investigating compounds such as curcumin, resveratrol, and ginsenosides suggest promising adjunctive benefits when incorporated into established treatment regimens

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